apoptotic signaling pathway
The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.
Exact Synonyms
apoptotic signalling pathway
induction of apoptosis by extracellular signals
class Information
created_by
pr
creation_date
2011-11-23T09:30:23Z
has_alternative_id
has_obo_namespace
biological_process
never in taxon
class Relations
Subclass of
Related from
part of
positively regulates
negatively regulates
starts with