OntologiesgoclassesPR:000001094   
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rhodopsin-like G-protein coupled receptorImported
http://purl.obolibrary.org/obo/PR_000001094

A G-protein coupled receptor that contains the 7 transmembrane receptor (rhodopsin family) domain (Pfam:PF00001), which includes 7 transmembrane helices (TMI-TM7) with 3 intracellular loops (IL1-IL3) and 3 extracellular loops (EL1-EL3) between the helices. The amino-terminal region is extracellular and the carboxyl-terminal region is intracellular. Rhodopsin-like G-protein coupled receptors (GPCRs) are unique among the several classes of GPCRs in that most have a very short amino-terminal segment and several characteristic sequence motifs, particularly NSxxNPxxY in TM7 and D/E-R-Y/F between TM3 and loop IL2. Most bind their ligands within a cavity between the TM regions.

Defined bypr
Also appears inhcaoclopclmaxouberon + 6
Exact Synonyms
class 1 G-protein coupled receptor
class A G-protein coupled receptor
fam:rhodopsin
class Information
class Relations