macrophageImported
A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.
Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid.
Defined bycl
Exact Synonyms
histiocyte
class Information
has_dbxref
- macrophagebto
- CALOHA:TS-0587
- Macrophagefma
- Histiocytefma
- MESH:D008264
preferred label
- Histiocyte
- Macrophage
present in taxon
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Equivalent to
Subclass of
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occurs in
results in acquisition of features of
acts on population of
results in movement of
has input