integrin alpha-MImported
An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1.
Category=gene. Requested by=CL.
Defined bypr
Exact Synonyms
CD11 antigen-like family member B
CD11b
cell surface glycoprotein MAC-1 subunit alpha
CR-3 alpha chain
ITGAM
leukocyte adhesion receptor MO1
neutrophil adherence receptor
Related Synonyms
CD11B
CR3A
class Information
class Relations
Subclass of
Related from
lacks_plasma_membrane_part
- hematopoietic stem cellcl
- mast cell progenitorcl
- hematopoietic multipotent progenitor cellcl
- proerythroblastcl
- thymic plasmacytoid dendritic cellcl
- erythroblastcl
- hematopoietic oligopotent progenitor cell, lineage-negativecl
- megakaryocyte progenitor cellcl
- CD8-alpha-positive CD11b-negative dendritic cellcl
- CD8-alpha-negative CD11b-negative dendritic cellcl
- basophil progenitor cellcl
- group 2 innate lymphoid cell, mousecl
- common dendritic progenitorcl
- erythroid progenitor cell, mammaliancl
- natural helper lymphocytecl
- promyelocytecl
- pre-conventional dendritic cellcl
- splenic marginal zone macrophagecl
- thymic conventional dendritic cellcl
- CD11c-low plasmacytoid dendritic cellcl
- reticulocytecl
- eosinophil progenitor cellcl
has high plasma membrane amount
- CD27-high, CD11b-high natural killer cell, mousecl
- CD11b-high, CD103-negative, langerin-negative lymph node dendritic cellcl
- peritoneal macrophagecl
- liver CD103-negative dendritic cellcl
- lymphoid MHC-II-negative classical monocytecl
- CD103-negative, langerin-positive lymph node dendritic cellcl
- CD27-low, CD11b-high natural killer cell, mousecl
- lymphoid MHC-II-negative non-classical monocytecl
has low plasma membrane amount
- splenic red pulp macrophagecl
- Kupffer cellcl
- liver CD103-positive dendritic cellcl
- CD11b-low, CD103-negative, langerin-negative lymph node dendritic cellcl
- CD103-positive, langerin-positive lymph node dendritic cellcl
- lymph node macrophagecl
- CD27-high, CD11b-low natural killer cell, mousecl
- alveolar macrophagecl
- CD27-low, CD11b-low immature natural killer cell, mousecl
lacks_plasma_membrane_part