susceptibility to respiratory infections associated with CD8alpha chain mutation
Susceptibility to respiratory infections associated with CD8 alpha chain mutation is a rare primary immunodeficiency due to a defect in adaptive immunity characterized by the absence of CD8+ T cells with normal immunoglobulin and specific antibody titres in blood and susceptibility to recurrent respiratory bacterial and viral infections. Symptom severity range from fatal respiratory insufficiency to mild or asymptomatic phenotypes.
Exact Synonyms
familial CD8 deficiency
susceptibility to respiratory infections associated with CD8alpha chain mutation
Related Synonyms
CD8 deficiency, familial
class Information
curated content resource
https://search.clinicalgenome.org/kb/conditions/MONDO:0012161
excluded subClassOf
has exact match
has_dbxref