Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. These cells are distinct from natural killer cells and from killer cells mediating antibody-dependent cell cytotoxicity.
class Information
A type of immune cell that can kill certain cells, including foreign cells, cancer cells, and cells infected with a virus. Cytotoxic T lymphocytes can be separated from other blood cells, grown in the laboratory, and then given to a patient to kill cancer cells. A cytotoxic T lymphocyte is a type of white blood cell and a type of lymphocyte.
C12543
CTRP
Cytotoxic T-Lymphocyte
Cytotoxic_T-Lymphocyte
Cytotoxic T-Lymphocyte
Cell
C0039195
class Relations
- PR-54 (ras-13 Asp) Peptide
- Autologous Anti-MART-1 F5 T-Cell Receptor Gene-Engineered Peripheral Blood Lymphocytes
- hTERT-encoding DNA Vaccine INVAC-1
- Long PD-L1 Peptide Vaccine
- MVA-BN Smallpox Vaccine
- Sipuleucel-T
- Anti-GD2/Anti-CD56 4SCAR-expressing Bispecific T-cells
- Human gp100 Plasmid DNA Vaccine
- Autologous Anti-GD2/Anti-PSMA 4SCAR-expressing Bispecific T-cells
- Melanoma Tumor-Reactive Autologous Tumor Infiltrating Lymphocyte
- Lorukafusp alfa
- WT1 Analog Peptide Vaccine
- MAGE-A3 Reactive T Cell Receptor-transduced Autologous T Cells
- gp100: ES209-217(210M) Peptide
- Immunocytokine NHS-IL12
- Carcinoembryonic Antigen Peptide 1-6D
- Anti-CD19 CAR-IL-18-expressing Autologous T-lymphocytes
- Anti-CD137 Agonistic Monoclonal Antibody AGEN2373
- Recombinant Vaccinia-CEA
- HPV 16 E7 Antigen-expressing Lactobacillis casei Vaccine BLS-ILB-E710c
- Arginase-1 Long Peptide Vaccine
- Fowlpox-PSA-TRICOM Vaccine
- hVEGF26-104/RFASE Peptide Vaccine
- IDH1R132H-Specific Peptide Vaccine PEPIDH1M
- Urelumab
- gp100:209-217(210M) Peptide Vaccine
- Alpha-type-1 Polarized Dendritic Cells
- Microparticle-encapsulated CYP1B1-encoding DNA Vaccine ZYC300
- PCLUS 3-18MN
- Autologous Anti-B7-H3 CAR T Cells
- Exlinkibart
- Recombinant Vaccinia-MUC-1 Vaccine
- 117-126:FGF-5 Peptide
- Prostatic Acid Phosphatase-Sargramostim Fusion Protein PA2024
- MART-1:26-35(27L) Peptide Vaccine
- Incomplete Freund's Adjuvant
- Tyrosinase:240-251(244S) Peptide
- PSA:154-163(155L) Peptide Vaccine
- PCLUS 6.1-18MN
- K-RAS ASP-13 Mutant Protein
- ESO-1 Reactive Autologous Tumor Infiltrating Lymphocyte
- Recombinant Vaccinia PSA Vaccine
- gp100:280-288(288V) Peptide Vaccine
- Lifileucel
- Anti-CD137 Agonistic Monoclonal Antibody ADG106
- Recombinant dHER2 Vaccine
- PR1 Leukemia Peptide Vaccine
- Tyrosinase:146-156 Peptide
- gp100-Pulsed Peripheral Blood Mononuclear Cell
- ALVAC-B7-CEA
- Recombinant Fowlpox-gp100p209
- Autologous HER2-specific/EGFRt-expressing CD4/CD8-positive CAR T-cells
- Therapeutic Autologous Dendritic Cells
- gp100 and GM-CSF DNA/Gold Vaccine
- Therapeutic Autologous Lymphocytes
- Adenovirus Encoding Rat HER-2/neu
- gp100 Adenovirus Vaccine
- pBCAR3/pIRS2-Phosphopeptide-tetanus Peptide Vaccine
- Anti-OX40 Monoclonal Antibody
- Vaccinia-Tyrosinase Vaccine
- H3K27M Long Peptide Vaccine
- Tyrosinase:206-214 Peptide
- Rilimogene Galvacirepvec
- Recombinant Fowlpox-Tyrosinase Vaccine
- DNAJB1-PRKACA Fusion Kinase Peptide Vaccine
- Recombinant Fowlpox-CEA(6D)/TRICOM Vaccine
- gp100 Protein (184V)
- Renal Tumor-Reactive Autologous Peripheral Blood Lymphocyte
- Anti-GD2/Anti-CD70 4SCAR-expressing Bispecific T-cells
- Multipeptide Vaccine S-588210
- KLH-Lymphoma Ig Vaccine
- Recombinant Vaccinia-B7.1 Vaccine
- gp100:17-25 Peptide
- Axalimogene Filolisbac
- ALVAC-CEA (VCP248)
- FGF-5:172-176 / 217-220 Peptide
- Tertomotide
- Anti-p53 T-Cell Receptor-Transduced Peripheral Blood Lymphocytes
- VHL2 (Y12M) Peptide
- B7 Transfected Melanoma Cell Vaccine
- PR18 (ras-12CYS) Peptide
- Lenzilumab
- TRP-2: 180-188 Peptide
- Anti-PSMA/Anti-CD70 4SCAR-expressing Bispecific T-cells
- Autologous PD-1-targeted Chimeric Switch Receptor-modified T Lymphocytes
- Monoclonal Antibody 95-6-22
- PR-5V10 (ras-12 Val) Peptide
- Anti-GRP78 Monoclonal Antibody PAT-SM6
- Autologous AXL-targeted CAR T-cells CCT301-38
- DPT/BCG/Measles/Serratia/Pneumococcus Vaccine
- LMP-2:419-427 Peptide Vaccine
- Autologous Cytoplasmic Activated PD-1 CAR T-cells
- EF-1 Peptide
- Autologous Tumor Infiltrating Lymphocytes ITIL-168
- Verpasep Caltespen
- Autologous Anti-gp100:154-162 TCR Tumor Infiltrating Lymphocytes
- E1M(184V) Peptide Vaccine
- Renal Tumor-Reactive Autologous Tumor Infiltrating Lymphocyte
- MART-1 Vaccinia Vaccine
- Ras Peptide ASP
- Anti-gp100 TCR Retroviral Vector-Transduced Autologous TIL
- MART-1 Fowlpox Vaccine
- Gag:267-274 Peptide Vaccine
- Ipilimumab
- Autologous Anti-gp100:154-162 T-Cell Receptor Gene-Engineered Peripheral Blood Lymphocytes
- Ras Peptide VAL
- DPT/Typhoid/Staphylococcus aureus/Paratyphoid A/Paratyphoid B Vaccine
- Recombinant Vaccinia-TRICOM Vaccine
- Galinpepimut-S
- VHL16 Peptide
- PAX3/FKHR Peptide Vaccine
- Anti-CD20 Monoclonal Antibody BAT4306F
- pIRS2 Phosphopeptide-tetanus Peptide Vaccine
- Rilimogene Galvacirepvec/Rilimogene Glafolivec
- Autologous Anti-mesothelin TCR-expressing T-cells FH-TCR TMSLN
- PR7V10 (ras-12 Ala) Peptide
- gp100-Reactive Autologous Peripheral Blood Lymphocyte
- Alefacept
- Tyrosinase Peptide
- Recombinant Fowlpox-TRICOM Vaccine
- MAGE-A3-expressing Adenovirus Type 5 Vaccine
- Daromun
- 27-35(27L):MART-1 Peptide
- Synthetic Long E6 Peptide-Toll-like Receptor Ligand Conjugate Vaccine ISA201
- Attenuated Live Listeria monocytogenes Encoding KRAS G12D
- Evunzekibart
- Autologous Memory Cytokine-enriched Natural Killer Cells
- HPV Types 16/18 E6/E7-Adenoviral Transduced Autologous Lymphocytes/alpha-Galactosylceramide Vaccine BVAC-C
- FrSh61 (MEA) VHL33 Peptide
- Binetrakin
- Ras Peptide CYS
- Obinutuzumab
- Autologous Anti-BCMA CAR-transduced T-cells KITE-585
- VHL-59: 116-128 Peptide
- Autologous Tumor Infiltrating Lymphocytes MDA-TIL
- Recombinant Vaccinia-CEA(6D)-TRICOM Vaccine
- Telomerase: 540-548 Peptide Vaccine
- Tyrosinase:368-376(370D) Peptide
- VHL-42: 65-76(V74G) Peptide
- Autologous Anti-B7-H3 CAR T Cells CAR.B7-H3T
- MART-1:27-35 Peptide Vaccine
- Berzofsky Ras/P53 Peptide Vaccine
- Synthetic Long HPV16 E6/E7 Peptides Vaccine ISA101b
- HPV 16 E7:12-20 Peptide Vaccine
- EF-2 Peptide
- p53 Peptide Vaccine MPS-128
- Recombinant Vaccinia-Mgp100 Vaccine
- SBIL-2 Transduced Autologous Tumor-Infiltrating Lymphocyte
- HPV 16 E7:86-93 Peptide Vaccine
- Anti-GD2/PSMA/CD276 4SCAR-expressing T-cells
- Anti-MART-1 TCR Retroviral Vector-Transduced Autologous TIL
- Autologous Clonal Neoantigen T Cells ATL001
- Anti-gp100 TCR Retroviral Vector-Transduced Autologous PBL
- PR-151 Peptide
- Autologous Anti-HLA-A*0201/AFP CAR T-cells ET1402L1
- MAGE-3 Peptide Vaccine
- Pooled Mutant KRAS-Targeted Long Peptide Vaccine
- Synthetic Long E6/E7 Peptides Vaccine HPV-01
- K-RAS GLY-12 Mutant Protein
- Long Peptide Vaccine 7
- Autologous Anti-MART-1 F5 TCR Tumor Infiltrating Lymphocytes
- MART-1 Adenovirus Vaccine
- Autologous Anti-EGFRvIII 4SCAR-IgT Cells
- MAGE-A1-specific T Cell Receptor-transduced Autologous T-cells
- gp100:209-217 Peptide
- Autologous MAGE-A10-specific HLA-A2-restricted TCR c796 Gene-engineered Lymphocytes
- CHP-HER-2 Peptide Vaccine
- PR6V10 (ras-12 Asp) Peptide
- TRP1(0RF3):1-9 Peptide
- KRAS CYS-12 Mutant Protein
- HPV 18 E6:13-21 Peptide
- HLA-B44-Restricted Tyrosinase Peptide
- Autologous Tumor Infiltrating Lymphocytes TBio-4101
- Recombinant Fowlpox-B7.1 Vaccine
- Brachyury-expressing Modified Vaccinia Ankara-TRICOM Vaccine
- Recombinant Vaccinia-gp100:209-217
- PSA:154-163 Peptide
- HPV 16 E6 (18-26) Peptide
- ESO-1:157-165(165V) Peptide
- VHL14 Peptide
- P53-Synthetic Long Peptides Vaccine
- Anti-CD137 Agonistic Monoclonal Antibody CTX-471
- Personalized Liposomal Neoantigen-based Peptide Vaccine EVX-01
- HPV16 Vaccine
- Autologous Anti-BCMA CD8+ CAR T-cells Descartes-11
- gp100:154-162 Peptide Vaccine
- NY-ESO-1 Plasmid DNA Cancer Vaccine pPJV7611
- gp100-Reactive Autologous Tumor Infiltrating Lymphocyte
- UV1 Telomerase Peptide Vaccine
- Autologous Natural Killer Cells SNK01
- IDH1R132H Mutation-targeting IDH1 Peptide Vaccine
- gp100:280-288 Peptide Vaccine
- Anti-CD137 Agonistic Monoclonal Antibody EU101
- K-RAS ASP-12 Mutant Protein
- Immunocytokine NHS-IL2-LT
- hTERT Multipeptide/Montanide ISA-51 VG/Imiquimod Vaccine GX 301
- (H115D)VHL35 Peptide
- LMP-2:340-349 Peptide Vaccine
- 2G-1 TCR Retroviral Vector-Transduced Lymphocytes
- Recombinant Fowlpox-Prostate Specific Antigen Vaccine
- Inalimarev
- MUC-1 Peptide Vaccine
- pBCAR3 Phosphopeptide-tetanus Peptide Vaccine
- Unconjugated Myeloma Ig Id
- G250 Peptide Vaccine
- K-RAS VAL-12 Mutant Protein
- Autologous Anti-CD19 CAR-expressing T Lymphocytes
- Differentiated Anti-BCMA Autologous CAR T Cells ARI0002h
- ESO-1 (161-180) Peptide Vaccine
- ESO-1 Reactive Autologous Peripheral Blood Lymphocyte
- Falimarev