OntologiesncitclassesNCIT:C12543   
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Cytotoxic T-Lymphocyte
http://purl.obolibrary.org/obo/NCIT_C12543

Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. These cells are distinct from natural killer cells and from killer cells mediating antibody-dependent cell cytotoxicity.

Exact Synonyms
CTL
Cytolytic T-Cell
cytotoxic T cell
Cytotoxic T Cell
Cytotoxic T Cells
Cytotoxic T lymphocyte
cytotoxic T lymphocyte
Cytotoxic T-Lymphocyte
Cytotoxic T-Lymphocytes
killer T cell
T-Lymphocyte, Cytotoxic
T-Lymphocytes, Cytotoxic
class Information
ALT_DEFINITION

A type of immune cell that can kill certain cells, including foreign cells, cancer cells, and cells infected with a virus. Cytotoxic T lymphocytes can be separated from other blood cells, grown in the laboratory, and then given to a patient to kill cancer cells. A cytotoxic T lymphocyte is a type of white blood cell and a type of lymphocyte.

code

C12543

Contributing_Source

CTRP

Display_Name

Cytotoxic T-Lymphocyte

Legacy Concept Name

Cytotoxic_T-Lymphocyte

Preferred_Name

Cytotoxic T-Lymphocyte

Semantic_Type

Cell

UMLS_CUI

C0039195

class Relations
Related from
Chemical_Or_Drug_Affects_Cell_Type_Or_Tissue
Gene_Product_Has_Associated_Anatomy