Pleckstrin Homology Domain-Containing Family G Member 5
Pleckstrin homology domain-containing family G member 5 (1062 aa, ~117 kDa) is encoded by the human PLEKHG5 gene. This protein plays a role in the activation of transforming protein RhoA and nuclear factor kappa B signaling pathways.
Exact Synonyms
GEF720
Guanine Nucleotide Exchange Factor 720
PH Domain-Containing Family G Member 5
Pleckstrin Homology Domain- and RhoGEF Domain-Containing Protein G5
Pleckstrin Homology Domain-Containing Family G Member 5
Pleckstrin Homology Domain-Containing Protein, Family G. Member 5
PLEKHG5
Synectin-Binding Guanine Exchange Factor
class Information
code
C150303
OMIM_Number
611101
Preferred_Name
Pleckstrin Homology Domain-Containing Family G Member 5
Semantic_Type
- Amino Acid, Peptide, or Protein
- Enzyme
Swiss_Prot
O94827
UMLS_CUI
C2001300
class Relations
Subclass of
- Guanine Nucleotide Exchange Factor
- Gene_Product_Has_Associated_AnatomysomePlasma Membrane
- Gene_Product_Expressed_In_TissuesomePeripheral Nervous System
- Gene_Product_Has_Structural_Domain_Or_MotifsomeDH Domain
- Gene_Product_Has_Structural_Domain_Or_MotifsomePH Domain
- Gene_Product_Plays_Role_In_Biological_ProcesssomeSignal Transduction
- Gene_Product_Plays_Role_In_Biological_ProcesssomeG Protein-Coupled Receptor Signaling
- Gene_Product_Encoded_By_GenesomePLEKHG5 Gene