OntologiesncitclassesNCIT:C20141   
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Soluble Guanylate Cyclase
http://purl.obolibrary.org/obo/NCIT_C20141

Human Soluble Guanylate Cyclases (Adenylyl Cyclase 4/Guanylyl Cyclase Family) are heterodimeric (alpha/beta) nitric oxide-activated cytoplasmic enzymes that catalyze conversion of GTP to cGMP second messenger. The main receptors for nitric oxide in the cardiovascular system and for nitrovasodilator drugs, alpha/beta interaction is required for guanylyl cyclase activity. (NCI)

Exact Synonyms
EC 4.6.1.2
Guanylate Cyclase, Soluble
GUCY
sGC
Soluble Guanylate Cyclase
Soluble Guanylyl Cyclase
class Information
code

C20141

DesignNote

Protein_Plays_Role_In_Biological_Process: cGMP Synthesis

Legacy Concept Name

Soluble_Guanylate_Cyclase

Preferred_Name

Soluble Guanylate Cyclase

Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Enzyme
UMLS_CUI

C1097411

class Relations