Inhibin
Inhibins are peptide hormones, secreted by the follicular cells of the ovary and by the testis, that negatively regulate the synthesis and secretion of follicle stimulating hormone from the anterior pituitary. The detection of serum inhibins has been implicated in association with reproductive disorders, including infertility and ovarian cancers.
Exact Synonyms
Folliculostatin
Inhibin Hormone
Inhibin
class Information
CAS_Registry
57285-09-3
code
C2276
DesignNote
Both inhibin A and inhibin B are heterodimers consisting of an alpha subunit and a beta A or beta B subunit linked by disulphide bonds. Both inhibins function as negative regulators for FSH synthesis and secretion. Furthermore, serum concentrations of inhibins transit from inhibin B to inhibin A dominance during menstrual cycle.
Legacy Concept Name
Inhibin
Preferred_Name
Inhibin
Semantic_Type
- Amino Acid, Peptide, or Protein
- Hormone
UMLS_CUI
C0021463
class Relations
Subclass of