OntologiesncitclassesNCIT:C2276   
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Inhibin
http://purl.obolibrary.org/obo/NCIT_C2276

Inhibins are peptide hormones, secreted by the follicular cells of the ovary and by the testis, that negatively regulate the synthesis and secretion of follicle stimulating hormone from the anterior pituitary. The detection of serum inhibins has been implicated in association with reproductive disorders, including infertility and ovarian cancers.

Exact Synonyms
Folliculostatin
Inhibin Hormone
Inhibin
class Information
CAS_Registry

57285-09-3

code

C2276

DesignNote

Both inhibin A and inhibin B are heterodimers consisting of an alpha subunit and a beta A or beta B subunit linked by disulphide bonds. Both inhibins function as negative regulators for FSH synthesis and secretion. Furthermore, serum concentrations of inhibins transit from inhibin B to inhibin A dominance during menstrual cycle.

Legacy Concept Name

Inhibin

Preferred_Name

Inhibin

Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Hormone
UMLS_CUI

C0021463

class Relations