Choriocarcinoma
An aggressive malignant tumor arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Approximately half of the cases develop from a complete hydatidiform mole. A minority of cases arise in the testis or the ovaries. There is often marked elevation of human chorionic gonadotropin (hCG) in the blood. Choriocarcinomas disseminate rapidly through the hematogenous route; the lungs are most frequently affected.
Exact Synonyms
chorioblastoma
CHORIOCARCINOMA, MALIGNANT
Choriocarcinoma, NOS
choriocarcinoma
Choriocarcinoma
Chorioepithelioma
chorioepithelioma
chorionic carcinoma
class Information
ALT_DEFINITION
- A malignant, fast-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to the uterus and help form the placenta). Almost all choriocarcinomas form in the uterus after fertilization of an egg by a sperm, but a small number form in a testis or an ovary. Choriocarcinomas spread through the blood to other organs, especially the lungs. They are a type of gestational trophoblastic disease.
- A malignant neoplasm arising from placental trophoblast cells. They generally arise in the uterus.
code
C2948
Contributing_Source
- CDISC
- CPTAC
- CTRP
- GDC
- PCDC
Display_Name
Choriocarcinoma
ICD-O-3_Code
9100/3
in_subset
- CTRP Disease Terminology
- CPTAC Neoplasms Codelist
- Mapped ICDO3.2 Morphology Terminology
- CDISC SEND Terminology
- GDC Terminology
- CTRP Terminology
- CDISC SEND Tumor Findings Results Terminology
- GCT Authorized Value Terminology
- NCIt Neoplasm Core Terminology
- Mapped ICDO3.2 Morphology PT Terminology
- GDC Value Terminology
- CPTAC Codelists Terminology
- Mapped ICDO3.2 Terminology
- Mapped ICDO3.1 Terminology
- Clinical Data Interchange Standards Consortium Terminology
- Mapped ICDO3.1 Morphology PT Terminology
- Mapped ICDO3.1 Morphology Terminology
- CTS-API Disease Main Type Terminology
- CPTAC Terminology
- Clinical Trials Search-Application Programming Interface Disease Category Terminology
- GCT Histology Table
- oncotree_slim
Is_PCDC_GCT_Authorized_Value_For_Variable
Is_Value_For_GDC_Property
Legacy Concept Name
Choriocarcinoma
Maps_To
- 9100/3
- Choriocarcinoma, NOS
- Chorioepithelioma
- Chorionepithelioma
Neoplasm_Has_Special_Category
Neoplastic_Status
Malignant
Preferred_Name
Choriocarcinoma
Semantic_Type
Neoplastic Process
UMLS_CUI
C0008497
class Relations
Equivalent to
- (CarcinomaandTrophoblastic TumorandDisease_Has_Abnormal_CellsomeMalignant Cytotrophoblastic CellandDisease_Has_Abnormal_CellsomeMalignant Syncytiotrophoblastic Giant CellandDisease_Has_Abnormal_CellsomeMalignant Intermediate Type Trophoblastic CellandDisease_Has_FindingsomeHuman Chorionic Gonadotropin-Positive Neoplastic Cells PresentandDisease_May_Have_FindingsomeHemorrhageandDisease_May_Have_FindingsomeNecrotic Change)
Subclass of