Essential Thrombocythemia
A chronic myeloproliferative neoplasm that involves primarily the megakaryocytic lineage. It is characterized by sustained thrombocytosis in the blood, increased numbers of large, mature megakaryocytes in the bone marrow, and episodes of thrombosis and/or hemorrhage. (WHO, 2008)
Exact Synonyms
Essential (hemorrhagic) thrombocythemia
Essential Thrombocytemia
essential thrombocythemia
Essential thrombocythemia
Essential Thrombocythemia
Essential Thrombocytosis
essential thrombocytosis
ET
Idiopathic Thrombocythemia
Idiopathic thrombocythemia
Primary Thrombocythemia
Primary Thrombocytosis
class Information
ALT_DEFINITION
- A chronic condition that involves primarily the megakaryocytic lineage. It is characterized by sustained thrombocytosis in the blood, increased numbers of large, mature megakaryocytes in the bone marrow, and elevated risk for thrombosis and/or hemorrhage.
- An increased number of thrombocytes (platelets) in the blood, without a known cause.
code
C3407
Contributing_Source
- Cellosaurus
- CPTAC
- CTEP
- CTRP
- GDC
- mCode
- NICHD
Display_Name
Essential Thrombocythemia
ICD-O-3_Code
9962/3
in_subset
- mCode Terminology
- Mapped ICDO3.1 Morphology PT Terminology
- Mapped ICDO3.1 Terminology
- mCode Primary Cancer Disorder Value Set
- Mapped ICDO3.1 Morphology Terminology
- GDC Value Terminology
- NCI CTEP SDC Chronic Myeloproliferative Disease Sub-Category Terminology
- Cellosaurus Terminology
- GDC Terminology
- Mapped ICDO3.2 Morphology Terminology
- CTRP Disease Terminology
- mCode Primary Malignant Neoplasm Disorder Value Set
- Pediatric Hematology-Oncology Terminology
- Mapped ICDO3.2 Terminology
- NCI CTEP Simplified Disease Classification Terminology
- NICHD Terminology
- CPTAC Terminology
- CPTAC Neoplasms Codelist
- CPTAC Codelists Terminology
- Cellosaurus Disease Terminology
- NCIt Neoplasm Core Terminology
- CTRP Terminology
- Mapped ICDO3.2 Morphology PT Terminology
- mCode Cancer Disorder Value Set
Is_Value_For_GDC_Property
Legacy Concept Name
Essential_Thrombocythemia
Maps_To
- 9962/3
- Essential (haemorrhagic) thrombocythaemia
- Essential hemorrhagic thrombocythaemia
- Essential thrombocythemia
- Idiopathic hemorrhagic thrombocythaemia
- Idiopathic thrombocythemia
Neoplastic_Status
Malignant
Preferred_Name
Essential Thrombocythemia
Semantic_Type
Neoplastic Process
UMLS_CUI
C0040028
class Relations
Equivalent to
- (Myeloproliferative Neoplasm, BCR-ABL1 NegativeandMegakaryocytic NeoplasmandDisease_Has_Normal_Cell_OriginsomeMultipotent Bone Marrow Stem CellandDisease_Has_Abnormal_CellsomeGiant PlateletandDisease_Has_Abnormal_CellsomeLarge Atypical PlateletandDisease_Has_Abnormal_CellsomeLarge MegakaryocyteandDisease_Has_Abnormal_CellsomeGiant MegakaryocyteandDisease_Has_FindingsomeMegakaryocytes Increased in Bone MarrowandDisease_Has_FindingsomeThrombocytosisandDisease_Has_FindingsomeChronic Clinical CourseandDisease_May_Have_Cytogenetic_AbnormalitysomeGain of Chromosome 8andDisease_May_Have_Cytogenetic_AbnormalitysomeLoss of Chromosome 13qandDisease_May_Have_FindingsomeHemorrhageandDisease_May_Have_FindingsomeHepatomegalyandDisease_May_Have_FindingsomeSplenomegalyandDisease_May_Have_FindingsomeHypercellular Bone MarrowandDisease_May_Have_Associated_DiseasesomeThrombosisandDisease_Excludes_Abnormal_CellsomeTear-Drop Red Blood CellandDisease_Excludes_FindingsomeLeukoerythroblastic ReactionandDisease_Excludes_FindingsomeBone Marrow Dysplasia PresentandDisease_Excludes_FindingsomeIncreased Red Cell MassandDisease_May_Have_Molecular_AbnormalitysomeMPL Gene MutationandDisease_May_Have_Molecular_AbnormalitysomeCALR Gene MutationandDisease_May_Have_Molecular_AbnormalitysomeJAK2 Gene Mutation)