gp100-Reactive Autologous Tumor Infiltrating Lymphocyte
Tumor infiltrating lymphocytes (TIL) isolated from a patient, exposed to the tumor-associated antigen gp100 in vitro, and then transferred back to the same patient to target tumor cells expressing gp100. gp100 human antigen is a wild-type self-antigen expressed by melanocytes, pigmented retinal cells and most melanomas. (NCI04)
Exact Synonyms
gp100-Reactive Autologous TIL
gp100-Reactive Autologous Tumor Infiltrating Lymphocyte
class Information
code
C38125
Has_Target
Legacy Concept Name
gp100-Reactive_Autologous_Tumor_Infiltrating_Lymphocyte
NSC Number
731217
Preferred_Name
gp100-Reactive Autologous Tumor Infiltrating Lymphocyte
Semantic_Type
- Cell
- Pharmacologic Substance
UMLS_CUI
C1515627
class Relations
Subclass of
- Therapeutic Tumor Infiltrating Lymphocytes Preparation
- Therapeutic Autologous Lymphocytes
- Chemical_Or_Drug_Has_Mechanism_Of_ActionsomeAntigen Sensitization
- Chemical_Or_Drug_Has_Physiologic_EffectsomeT-Cell Activation
- Chemical_Or_Drug_Has_Physiologic_EffectsomeImmunopotentiation
- Chemical_Or_Drug_Affects_Cell_Type_Or_TissuesomeCytotoxic T-Lymphocyte