Astroblastoma, MN1-Altered
A rare glial neoplasm characterized by structural rearrangements of the MN1 gene at chromosome band 22q12.1. It is usually found in the cerebral hemispheres of young adults and children and predominantly affects females. Morphologically, it consists of elongated glial cells with abundant eosinophilic cytoplasm and GFAP-positive processes, arranged perivascularly.
Exact Synonyms
Astroblastoma, MN1-Altered
Astroblastoma
class Information
code
C4324
Contributing_Source
GDC
ICD-O-3_Code
9430/3
in_subset
Is_Value_For_GDC_Property
Legacy Concept Name
Astroblastoma
Maps_To
- 9430/3
- Astroblastoma
Neoplastic_Status
Undetermined
Preferred_Name
Astroblastoma, MN1-Altered
Semantic_Type
Neoplastic Process
UMLS_CUI
C0334587
class Relations
Equivalent to
- (GliomaandDisease_Has_Molecular_AbnormalitysomeMN1 Gene RearrangementandDisease_Has_FindingsomePerivascular Pseudorosette FormationandDisease_May_Have_Cytogenetic_AbnormalitysomeMonosomy 22andDisease_May_Have_Cytogenetic_AbnormalitysomeMonosomy 10andDisease_May_Have_Cytogenetic_AbnormalitysomeMonosomy 21andDisease_May_Have_FindingsomeNecrotic ChangeandDisease_May_Have_FindingsomeWell-Circumscribed LesionandDisease_Mapped_To_GenesomeMN1 Gene)
Subclass of
Related from
Gene_Involved_In_Pathogenesis_Of_Disease