Post-Transplant Lymphoproliferative Disorder
Post-transplant lymphoproliferative disorder (PTLD) is a polyclonal (benign) or clonal (malignant) proliferation of lymphoid cells that develops as a consequence of immunosuppression in a recipient of a solid organ or bone marrow allograft. PTLDs comprise a spectrum ranging from early, Epstein-Barr virus (EBV)-driven polyclonal lymphoid proliferations to EBV-positive or EBV- negative lymphomas of predominantly B-cell or less often T-cell type. (WHO, 2001)
Exact Synonyms
Post transplant lymphoproliferative disorder, NOS
Post-transplant lymphoproliferative disorder (PTLD)
Post-transplant Lymphoproliferative Disorder
post-transplant lymphoproliferative disorder
Post-Transplant Lymphoproliferative Disorder
PTLD, NOS
PTLD
class Information
ALT_DEFINITION
- A condition in which a group of B-cells grow out of control after an organ transplant in patients with weakened immune systems. This usually happens if the patient has also been infected with Epstein-Barr virus. Post-transplant lymphoproliferative disorder may progress to non-Hodgkin lymphoma.
- Abnormal proliferation of B lymphocytes as a complication of immunosuppression occurring after solid organ or allogenic stem cell transplantation.
code
C4727
Contributing_Source
- CTRP
- GDC
- mCode
- MedDRA
- NICHD
Display_Name
Post-Transplant Lymphoproliferative Disorder
ICD-O-3_Code
9971/1
in_subset
- GDC Terminology
- Mapped ICDO3.2 Morphology Terminology
- NICHD Terminology
- CTRP Disease Terminology
- mCode Terminology
- mCode Cancer Disorder Value Set
- Mapped ICDO3.1 Terminology
- Mapped ICDO3.1 Morphology Terminology
- Pediatric Adverse Events Terminology
- Mapped ICDO3.2 Terminology
- mCode Primary Cancer Disorder Value Set
- CTRP Terminology
- Mapped ICDO3.1 Morphology PT Terminology
- Pediatric Adverse Events Terminology Mapped to MedDRA
- Mapped ICDO3.2 Morphology PT Terminology
- mCode Primary Malignant Neoplasm Disorder Value Set
- GDC Value Terminology
Is_Value_For_GDC_Property
Legacy Concept Name
Post-Transplant_Lymphoproliferative_Disorder
Maps_To
- 9971/1
- Post transplant lymphoproliferative disorder
- Post transplant lymphoproliferative disorder, NOS
- Post-transplant lymphoproliferative disorder, NOS
- PTLD, NOS
Preferred_Name
Post-Transplant Lymphoproliferative Disorder
Semantic_Type
Disease or Syndrome
UMLS_CUI
C0432487
class Relations
Equivalent to