SLAM Family Member 7
SLAM family member 7 (335 aa, ~37 kDa) is encoded by the human SLAMF7 gene. This protein is involved in signal transduction that promotes the activation of natural killer cells.
Exact Synonyms
CD Antigen CD319
CD2 Subset 1
CD2-Like Receptor Activating Cytotoxic Cells
CD2-Like Receptor-Activating Cytotoxic Cells
CD319 Antigen
CD319
CRACC
CS1
Membrane Protein FOAP-12
Novel Ly9
Protein 19A
SLAM Family Member 7
SLAMF7
class Information
code
C95308
Contributing_Source
CTRP
DesignNote
- SLAM family member 7 may be a target for elotuzumab in the treatment of multiple myeloma.
- There are 3 isoforms of SLAM family member 7 that result from alternative splicing. SLAM family member 7 isoform 3 is known as 19A24 protein and does not have the same natural killer cell activation activity as the canonical isoform 1. (UniProt)
Display_Name
SLAM Family Member 7
OMIM_Number
606625
Preferred_Name
SLAM Family Member 7
Semantic_Type
Amino Acid, Peptide, or Protein
Swiss_Prot
Q9NQ25
UMLS_CUI
C1099412