OntologiesncitclassesNCIT:C95308   
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SLAM Family Member 7
http://purl.obolibrary.org/obo/NCIT_C95308

SLAM family member 7 (335 aa, ~37 kDa) is encoded by the human SLAMF7 gene. This protein is involved in signal transduction that promotes the activation of natural killer cells.

Exact Synonyms
CD Antigen CD319
CD2 Subset 1
CD2-Like Receptor Activating Cytotoxic Cells
CD2-Like Receptor-Activating Cytotoxic Cells
CD319 Antigen
CD319
CRACC
CS1
Membrane Protein FOAP-12
Novel Ly9
Protein 19A
SLAM Family Member 7
SLAMF7
class Information
code

C95308

Contributing_Source

CTRP

DesignNote
  • SLAM family member 7 may be a target for elotuzumab in the treatment of multiple myeloma.
  • There are 3 isoforms of SLAM family member 7 that result from alternative splicing. SLAM family member 7 isoform 3 is known as 19A24 protein and does not have the same natural killer cell activation activity as the canonical isoform 1. (UniProt)
Display_Name

SLAM Family Member 7

OMIM_Number

606625

Preferred_Name

SLAM Family Member 7

Semantic_Type

Amino Acid, Peptide, or Protein

Swiss_Prot

Q9NQ25

UMLS_CUI

C1099412

class Relations