artesunateImported
An artemisinin derivative that is the hemisuccinate ester of the lactol resulting from the reduction of the lactone carbonyl group of artemisinin. It is used, generally as the sodium salt, for the treatment of malaria.
Defined bychebi
Exact Synonyms
4-oxo-4-{[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10-yl]oxy}butanoic acid
Related Synonyms
artesunate
artesunato
artesunatum
artesunic acid
AS
butanedioic acid, 1-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester
dihydroqinghasu hemsuccinate
class Information
charge
0
formula
C19H28O8
has_dbxref
- CAS:182824-33-5
- CAS:88495-63-0
- ChemIDplus:182824-33-5
- ChemIDplus:88495-63-0
- Chemspider:5293084
- DrugBank:DB09274
- Drug_Central:247
- HMDB:HMDB0240267
- KEGG DRUG:88495-63-0
- KEGG DRUG:D02482
- KEGG:D02482
- MeSH:C039726
- NCIt:C73005
- NIST Chemistry WebBook:88495-63-0
- PDBeChem:D95
- PMID:26097885
- PMID:30704910
- PMID:33652561
- PMID:33792170
- PMID:33814617
- PMID:33920029
- Reaxys:6003212
- SNOMEDCT:432555000
- SNOMEDCT:432410005
- Wikipedia:Artesunate
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16-,17-,18-,19-/m1/s1
inchikey
FIHJKUPKCHIPAT-AHIGJZGOSA-N
in_subset
mass
384.425
monoisotopicmass
384.17842
smiles
[H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@@]4(C)OO[C@@]13[C@]([H])(O[C@@H](OC(=O)CCC(O)=O)[C@@H]2C)O4