OntologiesprideclassesEFO:0000182   
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hepatocellular carcinomaImported
http://www.ebi.ac.uk/efo/EFO_0000182

A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation.

Defined byefo
Exact Synonyms
cancer, hepatocellular
carcinoma of liver cells
carcinoma of liver
carcinoma of the liver cells
carcinoma, hepatocellular, malignant
HCC
hepatoblastoma, somatic
hepatocellular adenocarcinoma
hepatocellular cancer, somatic
hepatocellular cancer
hepatocellular carcinoma, childhood type, somatic
hepatocellular carcinoma, somatic
hepatocellular carcinoma
hepatoma
liver and intrahepatic bile duct carcinoma
liver carcinoma
liver cell cancer (hepatocellular carcinoma)
liver cell carcinoma
primary carcinoma of liver cells
primary carcinoma of the liver cells
Related Synonyms
hepatoblastoma caused by somatic mutation
hepatoblastoma
liver and intrahepatic bile duct carcinoma
liver cancer
Narrow Synonyms
adult hepatoma
adult primary hepatocellular carcinoma
class Information
class Relations