negative cofactor 2 complexImported
A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A|H2B type present in the amino termini.
Defined bygo
class Information
has_obo_namespace
cellular_component
preferred label
negative cofactor 2 complex