bromfenacImported
Amfenac in which the the hydrogen at the 4 position of the benzoyl group is substituted by bromine. It is used for the management of ocular pain and treatment of postoperative inflammation in patients who have undergone cataract extraction. It was withdrawn from the US market in 1998, following concerns over off-label abuse and hepatic failure.
Defined bychebi
Exact Synonyms
[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
Related Synonyms
2-amino-3-(4-bromobenzoyl)benzeneacetic acid
bromfenac
bromfenaco
bromfenacum
[2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid
class Information
charge
0
formula
C15H12BrNO3
has_dbxref
- Beilstein:8335547
- CAS:91714-94-2
- DrugBank:DB00963
- Drug_Central:401
- KEGG:D07541
- LINCS:LSM-5585
- Patent:EP221753
- Patent:US4683242
- Wikipedia:Bromfenac
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C15H12BrNO3/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19/h1-7H,8,17H2,(H,18,19)
inchikey
ZBPLOVFIXSTCRZ-UHFFFAOYSA-N
in_subset
mass
334.16500
monoisotopicmass
333.00006
smiles
Nc1c(CC(O)=O)cccc1C(=O)c1ccc(Br)cc1
class Relations
Subclass of
Related from
is conjugate base of