darifenacinImported
2-[(3S)-1-Ethylpyrrolidin-3-yl]-2,2-diphenylacetamide in which one of the hydrogens at the 2-position of the ethyl group is substituted by a 2,3-dihydro-1-benzofuran-5-yl group. It is a selective antagonist for the M3 muscarinic acetylcholine receptor, which is primarily responsible for bladder muscle contractions, and is used as the hydrobromide salt in the management of urinary incontinence.
Defined bychebi
Also appears indron
Exact Synonyms
2-{(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2,2-diphenylacetamide
DARIFENACIN
Related Synonyms
(S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-alpha,alpha-diphenyl-3-pyrrolidineacetamide
darifenacin
class Information
charge
0
formula
C28H30N2O2
has_dbxref
- Beilstein:8449641
- CAS:133099-04-4
- DrugBank:DB00496
- Drug_Central:784
- KEGG:D03654
- LINCS:LSM-5995
- PMID:11831911
- PMID:14616424
- Wikipedia:Darifenacin
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C28H30N2O2/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26/h1-12,19,25H,13-18,20H2,(H2,29,31)/t25-/m1/s1
inchikey
HXGBXQDTNZMWGS-RUZDIDTESA-N
in_subset
mass
426.55000
monoisotopicmass
426.23073
smiles
[H][C@]1(CCN(CCc2ccc3OCCc3c2)C1)C(C(N)=O)(c1ccccc1)c1ccccc1