pizotifenImported
A benzocycloheptathiophene that is 9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene 4-ylidene)-1-methylpiperidine which is joined from the 4 position to the 4 position of an N-methylpiperidine moiety by a double bond. It is a sedating antihistamine, with strong serotonin antagonist and weak antimuscarinic activity. It is generally used as the malate salt for the treatment of migraine and the prevention of headache attacks during cluster periods.
Defined bychebi
Also appears indron
Exact Synonyms
4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine
Related Synonyms
pizotifen
pizotifene
pizotifeno
pizotifenum
Pizotyline
class Information
charge
0
formula
C19H21NS
has_dbxref
- CAS:15574-96-6
- Drug_Central:2220
- KEGG:D05523
- LINCS:LSM-3695
- Patent:BE636717
- Patent:US3272826
- Reaxys:753534
- Wikipedia:Pizotifen
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3
inchikey
FIADGNVRKBPQEU-UHFFFAOYSA-N
in_subset
mass
295.44278
monoisotopicmass
295.13947
smiles
CN1CCC(CC1)=C1c2ccccc2CCc2sccc12
class Relations
Subclass of
Related from
is conjugate acid of