loratadineImported
A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
Defined bychebi
Exact Synonyms
ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate
Related Synonyms
4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester
Aerotina
Alarin
Alavert
Alerpriv
Allerclear
Civeran
Claratyne
Claritin
Loracert
Loradamed
Loradex
Lorastine
loratadina
loratadine
loratadinum
Loratyne
Wal-itin
class Information
charge
0
formula
C22H23ClN2O2
has_alternative_id
has_dbxref
- CAS:79794-75-5
- Chemspider:3820
- DrugBank:DB00455
- Drug_Central:1605
- FooDB:FDB023577
- HMDB:HMDB0005000
- KEGG:D00364
- LINCS:LSM-5891
- PMID:15627436
- PMID:24134630
- PMID:31315424
- PMID:31576110
- PMID:32312261
- PMID:32694422
- PMID:32877950
- PMID:33550204
- PMID:33673552
- PMID:33963858
- PMID:34121623
- PMID:34306392
- PMID:7522069
- Reaxys:4273483
- Wikipedia:Loratadine
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
inchikey
JCCNYMKQOSZNPW-UHFFFAOYSA-N
in_subset
mass
382.890
monoisotopicmass
382.14481
smiles
CCOC(=O)N1CCC(CC1)=C1C2=C(CCC3=C1N=CC=C3)C=C(Cl)C=C2
class Relations
Subclass of
- tertiary carboxamidechebi
- ethyl esterchebi
- organochlorine compoundchebi
- N-acylpiperidinechebi
- benzocycloheptapyridinechebi
- has rolerosomegeroprotectorchebi
- has rolerosomeH1-receptor antagonistchebi
- has rolerosomecholinergic antagonistchebi
- has rolerosomeanti-allergic agentchebi
- has functional parentsomedesloratadinechebi