tramadolImported
A racemate consisting of equal amounts of (R,R)- and (S,S)-tramadol. A centrally acting synthetic opioid analgesic, used (as the hydrochloride salt) to treat moderately severe pain. The (R,R)-enantiomer exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. Originally developed by Gruenenthal GmbH and launched in 1977, it was subsequently isolated from the root bark of the South African tree Nauclea latifolia.
Defined bychebi
Exact Synonyms
rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
Related Synonyms
(+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
CG-315E
E-265
tramadol
tramadolum
U-26225A
class Information
charge
0
formula
C16H25NO2
has_dbxref
- CAS:27203-92-5
- DrugBank:DB00193
- HMDB:HMDB0014339
- KEGG:C07153
- KEGG:D08623
- Patent:GB997399
- Patent:US3652589
- PMID:22674657
- PMID:22943675
- PMID:22964800
- PMID:23031839
- PMID:23061925
- PMID:23095734
- PMID:23098678
- PMID:23099620
- PMID:23102445
- PMID:23145962
- PMID:23292128
- PMID:23328338
- PMID:23433451
- PMID:23543914
- PMID:23668411
- PMID:23755929
- PMID:23756535
- PMID:23773348
- PMID:23822079
- PMID:23825758
- PMID:23840975
- PMID:23843224
- PMID:23872384
- PMID:23907474
- PMID:23962470
- PMID:24014188
- PMID:25219922
- Reaxys:2943832
- Wikipedia:Tramadol
has_obo_namespace
chebi_ontology
in_subset
mass
263.37520
monoisotopicmass
263.18853
class Relations
Subclass of
- racematechebi
- has partbfosome(R,R)-tramadolchebi
- has partbfosome(S,S)-tramadolchebi
- has rolerosomeopioid analgesicchebi
- has rolerosomeadrenergic uptake inhibitorchebi
- has rolerosomexenobioticchebi
- has rolerosomeserotonergic antagonistchebi
- has rolerosomemuscarinic antagonistchebi
- has rolerosomenicotinic antagonistchebi
- has rolerosomeserotonin uptake inhibitorchebi
- has rolerosomeantitussivechebi
- has rolerosomemu-opioid receptor agonistchebi
- has rolerosomekappa-opioid receptor agonistchebi
- has rolerosomeNMDA receptor antagonistchebi
- has rolerosomedelta-opioid receptor agonistchebi
- has rolerosomecapsaicin receptor antagonistchebi
- has rolerosomeenvironmental contaminantchebi
- is conjugate base ofsometramadol(1+)chebi
Related from
is conjugate acid of