Entry status  (1)

REL

(6)

Experimental methods  (1)

X-ray diffraction

(6)

Authors  (33)

Greenblatt HM

(3)

Silman I

(3)

Sussman JL

(3)

Argaman A

(2)

Badet B

(2)

Botti S

(2)

Guenard D

(2)

Guillou C

(2)

Guénard D

(2)

Thal C

(2)

Bartolucci C

(1)

Burshteyn F

(1)

Cassidy M

(1)

Cassidy MS

(1)

Cheung J

(1)

Fels G

(1)

Franklin M

(1)

Franklin MC

(1)

Gary E

(1)

Gary EN

(1)

Hansen SB

(1)

Height J

(1)

Height JJ

(1)

Kryger G

(1)

Lamba D

(1)

Lewis T

(1)

Lewis TT

(1)

Love J

(1)

Perola E

(1)

Pilger C

(1)

Rudolph M

(1)

Rudolph MJ

(1)

Taylor P

(1)

Homo / hetero assembly  (1)

homo

(6)

Assembly composition  (1)

protein structure

(6)

Assembly polymer count  (2)

dimer

(5)

pentamer

(1)

Resolution distribution

2.0 - 2.5

(5)

2.5 - 3

(1)

Release year distribution

1995 - 2000

(2)

2000 - 2005

(3)

2005 - 2010

(1)

2010 - 2015

(1)

Journal  (5)

J Am Chem Soc

(2)

FEBS Lett

(1)

J Med Chem

(1)

J Mol Biol

(1)

Proteins

(1)

Organism superkingdom  (1)

Eukaryota

(6)

Organism name  (3)

Tetronarce californica

(4)

Aplysia californica

(1)

Homo sapiens

(1)

Molecule name  (4)

AChE

(5)

Acetylcholinesterase

(5)

Neurotransmitter-gated ion-channel ligand-binding domain-containing protein

(1)

Soluble acetylcholine receptor

(1)

Molecule type  (1)

Protein

(6)

Gene names  (2)

ache

(4)

ACHE

(1)

Interacting ligands  (8)

GNT : (-)-GALANTHAMINE

(6)

NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose

(4)

PG4 : TETRAETHYLENE GLYCOL

(2)

EDO : 1,2-ETHANEDIOL

(1)

FUC : alpha-L-fucopyranose

(1)

MG : MAGNESIUM ION

(1)

NO3 : NITRATE ION

(1)

PE8 : 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL

(1)

EC number / name  (1)

3.1.1.7 : Acetylcholinesterase

(5)

Biological function  (15)

acetylcholinesterase activity

(5)

carboxylic ester hydrolase activity

(5)

cholinesterase activity

(5)

hydrolase activity

(5)

acetylcholine binding

(1)

amyloid-beta binding

(1)

collagen binding

(1)

extracellular ligand-gated monoatomic ion channel activity

(1)

identical protein binding

(1)

laminin binding

(1)

monoatomic ion channel activity

(1)

protein binding

(1)

protein homodimerization activity

(1)

serine hydrolase activity

(1)

transmembrane signaling receptor activity

(1)

Biological process  (17)

acetylcholine catabolic process

(5)

acetylcholine catabolic process in synaptic cleft

(5)

choline metabolic process

(4)

acetylcholine receptor signaling pathway

(1)

amyloid precursor protein metabolic process

(1)

cell adhesion

(1)

monoatomic ion transmembrane transport

(1)

monoatomic ion transport

(1)

negative regulation of synaptic transmission, cholinergic

(1)

nervous system development

(1)

osteoblast development

(1)

positive regulation of cold-induced thermogenesis

(1)

positive regulation of protein secretion

(1)

receptor internalization

(1)

regulation of receptor recycling

(1)

retina development in camera-type eye

(1)

synapse assembly

(1)

Biological cell component  (13)

membrane

(6)

extracellular space

(5)

plasma membrane

(5)

side of membrane

(5)

synapse

(5)

synaptic cleft

(5)

Golgi apparatus

(1)

basement membrane

(1)

cell surface

(1)

extracellular region

(1)

neuromuscular junction

(1)

nucleus

(1)

perinuclear region of cytoplasm

(1)

SCOP fold  (1)

alpha/beta-Hydrolases

(4)

SCOP family  (1)

Acetylcholinesterase-like

(4)

CATH class  (2)

Alpha Beta

(5)

Mainly Beta

(1)

CATH topology  (2)

Rossmann fold

(5)

Acetylcholine Binding Protein; Chain: A,

(1)

Pfam accession / name  (2)

PF00135 : COesterase

(5)

PF02931 : Neur_chan_LBD

(1)

Diffraction protocol  (1)

Single wavelength

(6)

Diffraction radiation source type  (2)

Synchrotron

(4)

Rotating anode

(2)

Diffraction source  (5)

RIGAKU RUH3R

(2)

ALS BEAMLINE 8.2.1

(1)

ELETTRA BEAMLINE 5.2R

(1)

ESRF BEAMLINE ID14-2

(1)

NSLS BEAMLINE X29A

(1)

Synchrotron site  (4)

ALS

(1)

ELETTRA

(1)

ESRF

(1)

NSLS

(1)

Diffraction detector type  (2)

CCD

(3)

Image plate

(3)

Refinement software  (4)

CNS

(3)

PHENIX

(1)

REFMAC

(1)

X-PLOR

(1)

Representative Structures

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