Entry status  (1)

REL

(3)

Experimental methods  (2)

X-ray diffraction

(2)

Electron Microscopy

(1)

Authors  (46)

Baehr C

(1)

Chen H

(1)

Chen X

(1)

Cheng X

(1)

Guo S

(1)

He B

(1)

He X

(1)

Hewagama A

(1)

Hicks D

(1)

Jahan R

(1)

Jiang H

(1)

Jiang X

(1)

Jiang Y

(1)

Liban TL

(1)

Liu J

(1)

Liu M

(1)

Liu W

(1)

McGuire AT

(1)

Melcher K

(1)

Pancera M

(1)

Pancera MP

(1)

Petsko G

(1)

Pozharski E

(1)

Pravetoni M

(1)

Rao Q

(1)

Ringe D

(1)

Rodarte JV

(1)

Runyon S

(1)

Rupert PB

(1)

Shanafelt AB

(1)

Shen J

(1)

Strong RK

(1)

Wall A

(1)

Wang M

(1)

Wang MW

(1)

Wang X

(1)

Wang Y

(1)

Weidle C

(1)

Wilson MA

(1)

Xie X

(1)

Xu HE

(1)

Yang D

(1)

Yang J

(1)

Zhou Q

(1)

Zhou XE

(1)

Zhuang Y

(1)

Homo / hetero assembly  (1)

hetero

(3)

Assembly composition  (1)

protein/protein complex

(3)

Assembly polymer count  (2)

dimer

(2)

heptamer

(1)

Resolution distribution

1.5 - 2

(2)

3.0 - 3.5

(1)

Release year distribution

2000 - 2005

(1)

2020 - 2025

(2)

Journal  (3)

Cell

(1)

J Mol Biol

(1)

Structure

(1)

Organism superkingdom  (1)

Eukaryota

(3)

Organism name  (5)

Mus musculus

(2)

Bos taurus

(1)

Homo sapiens

(1)

Rattus norvegicus

(1)

synthetic construct

(1)

Molecule name  (22)

IG-heavy chain

(3)

IG-light lambda chain

(2)

Adenylate cyclase-inhibiting G alpha protein

(1)

G gamma-I

(1)

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

(1)

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

(1)

Guanine nucleotide-binding protein G(i) subunit alpha-1

(1)

HY4-1F9 Fab Heavy Chain

(1)

HY4-1F9 Fab Light Chain

(1)

IG-light kappa chain

(1)

Ig lambda-1 chain V regions MOPC 104E/RPC20/J558/S104

(1)

Ig-like domain-containing protein

(1)

M-OR-1

(1)

MOP

(1)

MOR-1

(1)

Mu opiate receptor

(1)

Mu opioid receptor

(1)

Mu-type opioid receptor

(1)

Transducin beta chain 1

(1)

Uncharacterized protein

(1)

hMOP

(1)

scFV16

(1)

Molecule type  (1)

Protein

(3)

Gene names  (7)

GNAI1

(1)

GNG2

(1)

Gm16747

(1)

Gnb1

(1)

Igh-VJ558

(1)

MOR1

(1)

OPRM1

(1)

Interacting Molecules  (9)

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

(1)

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

(1)

Guanine nucleotide-binding protein G(i) subunit alpha-1

(1)

HY4-1F9 Fab Heavy Chain

(1)

HY4-1F9 Fab Light Chain

(1)

Ig lambda-1 chain V regions MOPC 104E/RPC20/J558/S104

(1)

Ig-like domain-containing protein

(1)

Mu-type opioid receptor

(1)

scFV16

(1)

Interacting ligands  (4)

MOI : (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL

(3)

ACT : ACETATE ION

(1)

CLR : CHOLESTEROL

(1)

SO4 : SULFATE ION

(1)

Biological function  (29)

D2 dopamine receptor binding

(1)

G protein activity

(1)

G protein-coupled opioid receptor activity

(1)

G protein-coupled receptor activity

(1)

G protein-coupled receptor binding

(1)

G protein-coupled serotonin receptor binding

(1)

G-protein alpha-subunit binding

(1)

G-protein beta-subunit binding

(1)

G-protein beta/gamma-subunit complex binding

(1)

GDP binding

(1)

GTP binding

(1)

GTPase activity

(1)

GTPase binding

(1)

adenylate cyclase inhibitor activity

(1)

adenylate cyclase regulator activity

(1)

alkylglycerophosphoethanolamine phosphodiesterase activity

(1)

beta-endorphin receptor activity

(1)

guanyl nucleotide binding

(1)

hydrolase activity

(1)

magnesium ion binding

(1)

metal ion binding

(1)

morphine receptor activity

(1)

neuropeptide binding

(1)

nucleotide binding

(1)

protein binding

(1)

protein-containing complex binding

(1)

signaling receptor complex adaptor activity

(1)

spectrin binding

(1)

voltage-gated calcium channel activity

(1)

Biological process  (43)

G protein-coupled opioid receptor signaling pathway

(1)

G protein-coupled receptor signaling pathway

(1)

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

(1)

T cell migration

(1)

adaptive immune response

(1)

adenylate cyclase-activating dopamine receptor signaling pathway

(1)

adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

(1)

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

(1)

adenylate cyclase-inhibiting serotonin receptor signaling pathway

(1)

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

(1)

behavioral response to ethanol

(1)

calcium ion transmembrane transport

(1)

cardiac muscle cell apoptotic process

(1)

cell division

(1)

cell population proliferation

(1)

cellular response to catecholamine stimulus

(1)

cellular response to forskolin

(1)

cellular response to hypoxia

(1)

cellular response to morphine

(1)

cellular response to prostaglandin E stimulus

(1)

immune response

(1)

immune system process

(1)

negative regulation of Wnt protein secretion

(1)

negative regulation of cell population proliferation

(1)

negative regulation of insulin secretion

(1)

neuropeptide signaling pathway

(1)

phospholipase C-activating G protein-coupled receptor signaling pathway

(1)

positive regulation of ERK1 and ERK2 cascade

(1)

positive regulation of cholesterol biosynthetic process

(1)

positive regulation of cytosolic calcium ion concentration

(1)

positive regulation of neurogenesis

(1)

positive regulation of protein localization to cell cortex

(1)

positive regulation of relaxation of smooth muscle

(1)

regulation of NMDA receptor activity

(1)

regulation of cellular response to stress

(1)

regulation of mitotic spindle organization

(1)

response to peptide hormone

(1)

response to prostaglandin E

(1)

retina development in camera-type eye

(1)

sensory perception

(1)

sensory perception of pain

(1)

sensory perception of taste

(1)

signal transduction

(1)

Biological cell component  (30)

Golgi apparatus

(1)

axon

(1)

cell body

(1)

cell cortex

(1)

cell projection

(1)

centriolar satellite

(1)

centrosome

(1)

ciliary basal body

(1)

cytoplasm

(1)

cytoskeleton

(1)

cytosol

(1)

dendrite

(1)

endoplasmic reticulum

(1)

endosome

(1)

extracellular exosome

(1)

heterotrimeric G-protein complex

(1)

immunoglobulin complex

(1)

lysosomal membrane

(1)

membrane

(1)

midbody

(1)

neuron projection

(1)

nucleolus

(1)

nucleoplasm

(1)

nucleus

(1)

perikaryon

(1)

photoreceptor inner segment

(1)

photoreceptor outer segment

(1)

photoreceptor outer segment membrane

(1)

plasma membrane

(1)

synapse

(1)

SCOP fold  (1)

Immunoglobulin-like beta-sandwich

(1)

SCOP family  (2)

C1 set domains (antibody constant domain-like)

(1)

V set domains (antibody variable domain-like)

(1)

CATH class  (1)

Mainly Beta

(1)

CATH topology  (1)

Immunoglobulin-like

(1)

Pfam accession / name  (5)

PF00001 : 7tm_1

(1)

PF00400 : WD40

(1)

PF00503 : G-alpha

(1)

PF00631 : G-gamma

(1)

PF07686 : V-set

(1)

Diffraction protocol  (1)

Single wavelength

(2)

Diffraction radiation source type  (2)

Rotating anode

(1)

Synchrotron

(1)

Diffraction source  (2)

APS BEAMLINE 19-ID

(1)

RIGAKU RU300

(1)

Synchrotron site  (1)

APS

(1)

Diffraction detector type  (2)

Image plate

(1)

Pixel

(1)

Refinement software  (2)

PHENIX

(2)

CNS

(1)

EM microscope model  (1)

FEI TITAN KRIOS

(1)

EM detector name  (1)

GATAN K3 (6k x 4k)

(1)

Representative Structures

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