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Entries 1 to 10 of 85
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Crystal structure of White Spot Syndrome Virus Thymidylate Synthase - ternary complex with Methotrexate and dUMP
Panchal NV, Kumar S, Shaikh N, Vasudevan D
Int J Biol Macromol
(2021)
[PMID: 33197475 ]
Source organism: Shrimp white spot syndrome virus (isolate Tongan)
Assembly composition: protein only structure
Assembly name:
thymidylate synthase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-181211 (Preferred)
search this ID

Crystal structure of mutant V45A Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate and methotrexate
Keyunratsami K, Nualnoi T, Wongkamchai S, Songsiriritthigul C, Chen C-J, Canyuk B
To be published
Source organism: Brugia malayi
Assembly composition: protein only structure
Assembly name:
Thymidylate synthase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-105142 (Preferred)
search this ID

Crystal structure of wild type Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate and methotrexate
Keyunratsami K, Nualnoi T, Wongkamchai S, Songsiriritthigul C, Chen C-J, Canyuk B
To be published
Source organism: Brugia malayi
Assembly composition: protein only structure
Assembly name:
Thymidylate synthase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-105142 (Preferred)
search this ID

Enterococcus faecalis thymidylate synthase complex with methotrexate
Mangani S, Pozzi C
Eur J Med Chem
(2016)
[PMID: 27517810 ]
Source organism: Enterococcus faecalis
Assembly composition: protein only structure
Assembly name:
Thymidylate synthase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-182802 (Preferred)
search this ID

Crystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase in the Complex with Methotrexate from Campylobacter jejuni
Kim Y, Makowska-Grzyska M, Maltseva N, Grimshaw S, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)
To be published
Source organism: Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Assembly composition: protein only structure
Assembly name:
Bifunctional protein FolD
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-171038 (Preferred)
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Human thymidylate synthase in complex with dUMP and methotrexate
Chen D, Jansson A, Larsson A, Nordlund P
J Biol Chem
(2017)
[PMID: 28634233 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Thymidylate synthase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-138196 (Preferred)
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Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, FdUMP and 2-(2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)phenyl)acetic acid.
Czyzyk DJ, Valhondo M, Jorgensen WL, Anderson KS
Eur J Med Chem
(2019)
[PMID: 31536894 ]
Source organism: Cryptosporidium hominis
Assembly composition: protein only structure
Assembly name:
Bifunctional dihydrofolate reductase-thymidylate synthase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-102697 (Preferred)
search this ID

Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, FdUMP and 2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)benzoic acid
Czyzyk DJ, Valhondo M, Jorgensen WL, Anderson KS
Eur J Med Chem
(2019)
[PMID: 31536894 ]
Source organism: Cryptosporidium hominis
Assembly composition: protein only structure
Assembly name:
Bifunctional dihydrofolate reductase-thymidylate synthase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-102697 (Preferred)
search this ID

Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, FdUMP and 2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)-4-carbamoylbenzoic acid.
Czyzyk DJ, Valhondo M, Jorgensen WL, Anderson KS
Eur J Med Chem
(2019)
[PMID: 31536894 ]
Source organism: Cryptosporidium hominis
Assembly composition: protein only structure
Assembly name:
Bifunctional dihydrofolate reductase-thymidylate synthase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-102697 (Preferred)
search this ID

The high resolution structure of dihydrofolate reductase from Yersinia pestis complex with methotrexate as closed form
Chang C, Maltseva N, Kim Y, Makowska-Grzyska M, Mulligan R, Papazisi L, Anderson WF, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)
To be published
Source organism: Yersinia pestis CO92
Assembly composition: protein only structure
Assembly name:
Dihydrofolate reductase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-104916 (Preferred)
search this ID

...
Entries 1 to 10 of 85