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Entries 1 to 10 of 19
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Neutron crystal structure of human farnesyl pyrophosphate synthase in complex with risedronate
Yokoyama T, Mizuguchi M, Ostermann A, Kusaka K, Niimura N, Schrader TE, Tanaka I
J Med Chem
(2015)
[PMID: 26314394 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Farnesyl pyrophosphate synthase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146902 (Preferred)
search this ID

X-ray diffraction, Neutron Diffraction, Hybrid
1.402Å resolution
Released: 14 Oct 2015
DOI:
10.2210/pdb5cg5



Neutron crystal structure of human farnesyl pyrophosphate synthase in complex with risedronate and isopentenyl pyrophosphate
Yokoyama T, Mizuguchi M, Ostermann A, Kusaka K, Niimura N, Schrader TE, Tanaka I
J Med Chem
(2015)
[PMID: 26314394 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Farnesyl pyrophosphate synthase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146902 (Preferred)
search this ID

X-ray diffraction, Neutron Diffraction, Hybrid
1.7Å resolution
Released: 14 Oct 2015
DOI:
10.2210/pdb5cg6



F96M epi-isozizaene synthase: complex with 3 Mg2+ and risedronate
Ronnebaum TA, Gardner SM, Christianson DW
Biochemistry
(2020)
[PMID: 33270439 ]
Source organism: Streptomyces coelicolor
Assembly composition: protein only structure
Assembly name:
Epi-isozizaene synthase
(Preferred)
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PDBe complex ID:
PDB-CPX-191758 (Preferred)
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Wild-type epi-isozizaene synthase: complex with 3 Mg2+ and risedronate
Ronnebaum TA, Gardner SM, Christianson DW
Biochemistry
(2020)
[PMID: 33270439 ]
Source organism: Streptomyces coelicolor
Assembly composition: protein only structure
Assembly name:
Epi-isozizaene synthase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-191758 (Preferred)
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The role of threonine 201 and tyrosine 204 in the human farnesyl pyrophosphate synthase catalytic mechanism and the mode of inhibition by the nitrogen-containing bisphosphonates
Tsoumpra MK, Muniz JRC, Barnett BL, Kwaasi AA, Pilka ES, Kavanagh KL, Evdokimov A, Walter RL, Ebetino FH, von Delft F, Oppermann U, Russell RGG, Dunford JE
To be published
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Farnesyl pyrophosphate synthase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146902 (Preferred)
search this ID
T. Brucei Farnesyl Diphosphate Synthase Complexed with Risedronate
Cao R, Liu Y-L, Oldfield E
ACS Med Chem Lett
(2015)
[PMID: 25815158 ]
Source organism: Trypanosoma brucei
Assembly composition: protein only structure
Assembly name:
Farnesyl pyrophosphate synthase
(Preferred)
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PDBe complex ID:
PDB-CPX-183122 (Preferred)
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Cryptosporidium parvum putative polyprenyl pyrophosphate synthase (cgd4_2550) in complex with risedronate.
Chruszcz M, Artz JD, Dong A, Dunford J, Lew J, Zhao Y, Kozieradski I, Kavanaugh KL, Oppermann U, Sundstrom M, Weigelt J, Edwards AM, Arrowsmith CH, Bochkarev A, Hui R, Minor W, Structural Genomics Consortium (SGC)
Chem Biol
(2008)
[PMID: 19101474 ]
Source organism: Cryptosporidium parvum
Assembly composition: protein only structure
Assembly name:
Putative farnesyl pyrophosphate synthase
(Preferred)
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PDBe complex ID:
PDB-CPX-176918 (Preferred)
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Active Conformation of Farnesyl Pyrophosphate Synthase Bound to Isopentyl Pyrophosphate and Risedronate
Hosfield DJ, Zhang Y, Dougan DR, Brooun A, Tari LW, Swanson RV, Finn J
J Biol Chem
(2004)
[PMID: 14672944 ]
Source organism: Escherichia coli
Assembly composition: protein only structure
Assembly name:
Farnesyl diphosphate synthase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-149843 (Preferred)
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Structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with risedronate, dmapp and mg+2
Gabelli SB, McLellan JS, Montalvetti A, Oldfield E, Docampo R, Amzel LM
Proteins
(2006)
[PMID: 16288456 ]
Source organism: Trypanosoma cruzi
Assembly composition: protein only structure
Assembly name:
Farnesyl diphosphate synthase
(Preferred)
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PDBe complex ID:
PDB-CPX-186689 (Preferred)
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Human farnesyl diphosphate synthase complexed with Mg and risedronate
Kavanagh KL, Guo K, Von Delft F, Arrowsmith C, Sundstrom M, Edwards A, Oppermann U, Structural Genomics Consortium (SGC)
Proc Natl Acad Sci U S A
(2006)
[PMID: 16684881 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Farnesyl pyrophosphate synthase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146902 (Preferred)
search this ID

Entries 1 to 10 of 19