Function and Biology Details
Reaction catalysed:
(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
Ketol-acid reductoisomerase (NADP(+)) (preferred)
PDBe Complex ID:
PDB-CPX-138776 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ketol-acid reductoisomerase (NADP(+))
Molecule details ›
Chains: A, B, C, D
Length: 491 amino acids
Theoretical weight: 54.13 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 491 amino acids
Theoretical weight: 54.13 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P05793 (Residues: 1-491; Coverage: 100%)
Sequence domains:
- Acetohydroxy acid isomeroreductase, NADPH-binding domain
- Acetohydroxy acid isomeroreductase, catalytic domain
