2wwk

X-ray diffraction
1.7Å resolution

Crystal structure of the Titin M10-Obscurin like 1 Ig F17R mutant complex

Released:
Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-521909 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Obscurin-like protein 1 Chain: O
Molecule details ›
Chain: O
Length: 109 amino acids
Theoretical weight: 11.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75147 (Residues: 1-106; Coverage: 6%)
Gene names: KIAA0657, OBSL1
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins
Titin Chain: T
Molecule details ›
Chain: T
Length: 102 amino acids
Theoretical weight: 10.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WZ42 (Residues: 34252-34350; Coverage: 0%)
Gene name: TTN
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: C2
Unit cell:
a: 89.01Å b: 37.8Å c: 68.49Å
α: 90° β: 92.99° γ: 90°
R-values:
R R work R free
0.221 0.219 0.259
Expression system: Escherichia coli