› 2vx2

X-ray diffraction
2.3Å resolution

Crystal structure of human enoyl Coenzyme A hydratase domain- containing protein 3 (ECHDC3)

Released:
DOI: 10.2210/pdb2vx2/pdb
PDB entry 2vx2 coloured by chain, front view.
PDB entry 2vx2 coloured by chain, side view.
PDB entry 2vx2 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Yue WW, Guo K, Kochan G, Pilka E, Murray JW, Salah E, Cocking R, Sun Z, Roos AK, Pike ACW, Filippakopoulos P, Arrowsmith C, Wikstrom M, Edwards A, Bountra C, Oppermann U

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188433 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Enoyl-CoA hydratase domain-containing protein 3, mitochondrial Chains: A, B, C, D, E, F, G, H, I
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I
Length: 287 amino acids
Theoretical weight: 31.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96DC8 (Residues: 37-300; Coverage: 87%)
Gene names: ECHDC3, PP1494, PP8332
Sequence domains: Enoyl-CoA hydratase/isomerase
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: C2
Unit cell:
a: 235.756Å b: 135.296Å c: 83.871Å
α: 90° β: 98.84° γ: 90°
R-values:
R R work R free
0.172 0.17 0.22
Expression system: Escherichia coli BL21(DE3)

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