3dxm

X-ray diffraction
2.85Å resolution

Structure of Bos taurus Arp2/3 Complex with Bound Inhibitor CK0993548

Released:
Model geometry
Fit model/data

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero heptamer (preferred)
PDBe Complex ID:
PDB-CPX-108370 (preferred)
Entry contents:
7 distinct polypeptide molecules
Macromolecules (7 distinct):
Actin-related protein 3 Chain: A
Molecule details ›
Chain: A
Length: 418 amino acids
Theoretical weight: 47.43 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P61157 (Residues: 1-418; Coverage: 100%)
Gene names: ACTR3, ARP3
Sequence domains: Actin
Structure domains:
Actin-related protein 2 Chain: B
Molecule details ›
Chain: B
Length: 394 amino acids
Theoretical weight: 44.82 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: A7MB62 (Residues: 1-394; Coverage: 100%)
Gene names: ACTR2, ARP2
Sequence domains: Actin
Structure domains:
Actin-related protein 2/3 complex subunit 1B Chain: C
Actin-related protein 2/3 complex subunit 2 Chain: D
Actin-related protein 2/3 complex subunit 3 Chain: E
Actin-related protein 2/3 complex subunit 4 Chain: F
Actin-related protein 2/3 complex subunit 5 Chain: G

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 111.383Å b: 129.651Å c: 203.787Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.246 0.245 0.258