3gwm

X-ray diffraction
1.7Å resolution

Crystal structure of the holo-[Acyl-Carrier-Protein] Synthase (ACPS) from Mycobacterium smegmatis

Released:
Model geometry
Fit model/data
Entry authors: Poulsen C, Wilmanns M, Song YH

Function and Biology Details

Reaction catalysed:
CoA-(4'-phosphopantetheine) + an apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + an [acyl-carrier-protein]
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
PDBe Complex ID:
PDB-CPX-106411 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Holo-[acyl-carrier-protein] synthase Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.05 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
  • Canonical: A0R1H6 (Residues: 2-130; Coverage: 99%)
Gene names: MSMEG_4756, MSMEI_4636, acpS
Sequence domains: 4'-phosphopantetheinyl transferase superfamily
Structure domains: 4'-phosphopantetheinyl transferase domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: R3
Unit cell:
a: 67.45Å b: 67.45Å c: 86.06Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.174 0.172 0.203