4pv5

X-ray diffraction
2.3Å resolution

Crystal structure of mouse glyoxalase I in complexed with 18-beta-glycyrrhetinic acid

Released:
Model geometry
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Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-189993 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lactoylglutathione lyase Chains: A, B
Molecule details ›
Chains: A, B
Length: 183 amino acids
Theoretical weight: 20.7 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9CPU0 (Residues: 2-184; Coverage: 100%)
Gene name: Glo1
Sequence domains: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
Structure domains: 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OXFORD DIFFRACTION ENHANCE ULTRA
Spacegroup: P21
Unit cell:
a: 41.825Å b: 64.819Å c: 63.483Å
α: 90° β: 104.09° γ: 90°
R-values:
R R work R free
0.18 0.177 0.247
Expression system: Escherichia coli