5a9q

Electron Microscopy
23Å resolution

Human nuclear pore complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 304-mer (preferred)
PDBe Complex ID:
PDB-CPX-131100 (preferred)
Entry contents:
10 distinct polypeptide molecules
Macromolecules (10 distinct):
Nucleoporin Nup43 Chains: 0, 9, I, R
Molecule details ›
Chains: 0, 9, I, R
Length: 380 amino acids
Theoretical weight: 42.2 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q8NFH3 (Residues: 1-380; Coverage: 100%)
Gene name: NUP43
Sequence domains: WD domain, G-beta repeat
Nuclear pore complex protein Nup160 Chains: 1, J, S, a
Molecule details ›
Chains: 1, J, S, a
Length: 1436 amino acids
Theoretical weight: 162.28 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q12769 (Residues: 1-1436; Coverage: 100%)
Gene names: KIAA0197, NUP120, NUP160
Sequence domains: Nucleoporin Nup120/160
Nucleoporin Nup37 Chains: 2, K, T, b
Nuclear pore complex protein Nup133 Chains: 3, C, L, U
Nuclear pore complex protein Nup107 Chains: 4, D, M, V
Nuclear pore complex protein Nup96 Chains: 5, E, N, W
Protein SEC13 homolog Chains: 6, F, O, X
Nucleoporin SEH1 Chains: 7, G, P, Y
Nuclear pore complex protein Nup85 Chains: 8, H, Q, Z
Nuclear pore complex protein Nup155 Chains: A, B

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 23Å
Relevant EMDB volumes: EMD-3103