5gg6

X-ray diffraction
1.75Å resolution

Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGTP

Released:
Model geometry
Fit model/data

Function and Biology Details

Reactions catalysed:
8-oxo-GDP + H(2)O = 8-oxo-GMP + phosphate
P(1),P(4)-bis(5'-adenosyl)tetraphosphate + H(2)O = ATP + AMP
8-oxo-GTP + H(2)O = 8-oxo-GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-106333 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
8-oxo-(d)GTP phosphatase Chains: A, B
Molecule details ›
Chains: A, B
Length: 342 amino acids
Theoretical weight: 38.15 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
Expression system: Escherichia coli
UniProt:
  • Canonical: A0QUZ2 (Residues: 1-322; Coverage: 100%)
Gene names: MSMEG_2390, MSMEI_2330, mutT1
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 57.109Å b: 89.5Å c: 59.93Å
α: 90° β: 99.07° γ: 90°
R-values:
R R work R free
0.164 0.162 0.204
Expression system: Escherichia coli