6qau

X-ray diffraction
2.48Å resolution

Crystal structure of ULK2 in complexed with MRT67307

Released:
Model geometry
Fit model/data

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-184950 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase ULK2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 280 amino acids
Theoretical weight: 31.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8IYT8 (Residues: 1-276; Coverage: 27%)
Gene names: KIAA0623, ULK2
Sequence domains: Protein kinase domain

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P3121
Unit cell:
a: 117.006Å b: 117.006Å c: 141.485Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.198 0.196 0.237
Expression system: Escherichia coli BL21(DE3)