› 7e7z

Electron Microscopy
3.2Å resolution

CryoEM structure of the human Kv4.2-KChIP1 complex, transmembrane region

Released:
DOI: 10.2210/pdb7e7z/pdb
PDB entry 7e7z coloured by chain, front view.
PDB entry 7e7z coloured by chain, side view.
PDB entry 7e7z coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis of gating modulation of Kv4 channel complexes.
Kise Y, Kasuya G, Okamoto HH, Yamanouchi D, Kobayashi K, Kusakizako T, Nishizawa T, Nakajo K, Nureki O
OpenAccess logo Nature 599 158-164 (2021)
PMID: 34552243
Related structures: EMD-31005

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192791 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
A-type voltage-gated potassium channel KCND2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 255 amino acids
Theoretical weight: 28.33 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9NZV8 (Residues: 163-417; Coverage: 41%)
Gene names: KCND2, KIAA1044
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.2Å
Relevant EMDB volumes: EMD-31005
Expression system: Homo sapiens

Quick links

Citations

7 review citations

Sensing sound: Cellular specializations and molecular force sensors.
Qiu et al. (2022)
6 more