7m30

Electron Microscopy
3.81Å resolution

Cryo-EM structure of the HCMV pentamer bound by antibodies 1-103, 1-32 and 2-25

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero decamer (preferred)
PDBe Complex ID:
PDB-CPX-207854 (preferred)
Entry contents:
10 distinct polypeptide molecules
Macromolecules (10 distinct):
Envelope glycoprotein L Chain: B
Molecule details ›
Chain: B
Length: 248 amino acids
Theoretical weight: 27.66 KDa
Source organism: Human betaherpesvirus 5
Expression system: Homo sapiens
UniProt:
  • Canonical: P16832 (Residues: 31-278; Coverage: 100%)
Gene names: UL115, gL
Sequence domains: Cytomegalovirus glycoprotein L
Uncharacterized protein UL128 Chain: C
Molecule details ›
Chain: C
Length: 144 amino acids
Theoretical weight: 16.68 KDa
Source organism: Human betaherpesvirus 5
Expression system: Homo sapiens
UniProt:
  • Canonical: P16837 (Residues: 28-171; Coverage: 84%)
Gene name: UL128
Uncharacterized protein UL130 Chain: D
Protein UL131A Chain: E
2-25 Fab Heavy Chain Chain: F
2-25 Fab Light Chain Chain: G
1-32 Fab Heavy Chain Chain: H
1-32 Fab Light Chain Chain: L
1-103 Fab Heavy Chain Chain: M
1-103 Fab Light Chain Chain: N

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.81Å
Relevant EMDB volumes: EMD-23640
Expression system: Homo sapiens