7pgn

X-ray diffraction
2.4Å resolution

HHP-C in complex with glycosaminoglycan mimic SOS

Released:
Model geometry
Fit model/data

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-188709 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Hedgehog-interacting protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 470 amino acids
Theoretical weight: 52.5 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q96QV1 (Residues: 213-670; Coverage: 67%)
Gene names: HHIP, HIP, UNQ5825/PRO19644
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: GU4, YYJ
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P3121
Unit cell:
a: 100.56Å b: 100.56Å c: 311.88Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.192 0.19 0.227
Expression system: Homo sapiens