Function and Biology Details
Reactions catalysed:
SsDNA + n NTP = ssDNA/pppN(pN)(n-1) hybrid + (n-1) diphosphate
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- DNA-directed DNA polymerase, family B
- Nucleic acid-binding, OB-fold
- CST complex subunit Ten1, animal and plant type
- DNA polymerase alpha, subunit B
- DNA primase large subunit, eukaryotic/archaeal
- DNA primase, large subunit, eukaryotic
- DNA primase, small subunit, eukaryotic/archaeal
- Winged helix-like DNA-binding domain superfamily
23 more domains
Structure analysis Details
Assembly composition:
hetero octamer (preferred)
Assembly name:
DNA polymerase alpha:primase complex and DNA (preferred)
PDBe Complex ID:
PDB-CPX-122144 (preferred)
Entry contents:
7 distinct polypeptide molecules
1 distinct DNA molecule
1 distinct DNA molecule
Macromolecules (8 distinct):