7uil

Electron Microscopy
4.3Å resolution

Mediator-PIC Early (Tail A/B Dimer)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tridecamer (preferred)
PDBe Complex ID:
PDB-CPX-539105 (preferred)
Entry contents:
7 distinct polypeptide molecules
Macromolecules (7 distinct):
Mediator of RNA polymerase II transcription subunit 2 Chains: 1, b
Molecule details ›
Chains: 1, b
Length: 431 amino acids
Theoretical weight: 47.75 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q12124 (Residues: 1-431; Coverage: 100%)
Gene names: D2930, MED2, YDL005C
Sequence domains: Mediator complex subunit 2
Mediator of RNA polymerase II transcription subunit 3 Chains: 2, c
Molecule details ›
Chains: 2, c
Length: 397 amino acids
Theoretical weight: 43.12 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P40356 (Residues: 1-397; Coverage: 100%)
Gene names: HRS1, MED3, PGD1, YGL025C
Sequence domains: Mediator complex subunit 3 fungal
Mediator of RNA polymerase II transcription subunit 5 Chains: 3, e
Mediator of RNA polymerase II transcription subunit 14 Chains: 4, n
Mediator of RNA polymerase II transcription subunit 15 Chains: 5, o
Mediator of RNA polymerase II transcription subunit 16 Chains: 6, p
Mediator of RNA polymerase II transcription subunit 1 Chain: a

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.3Å
Relevant EMDB volumes: EMD-26548