7ur4

Electron Microscopy
3.34Å resolution

Cryo-EM Structure of the Neutralizing Antibody MPV467 in Complex with Prefusion Human Metapneumovirus F Glycoprotein

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-212418 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Fusion glycoprotein F0 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 551 amino acids
Theoretical weight: 60.49 KDa
Source organism: human metapneumovirus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q6WB98 (Residues: 1-490; Coverage: 91%)
Gene name: F
Sequence domains: Fusion glycoprotein F0
MPV467 Fab Heavy chain Chains: F, H, I
Molecule details ›
Chains: F, H, I
Length: 223 amino acids
Theoretical weight: 24.02 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
MPV467 Fab Light chain Chains: G, J, L

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.34Å
Relevant EMDB volumes: EMD-26704
Expression system: Homo sapiens