8ea0

Electron Microscopy
2.56Å resolution

CryoEM structure of miniGq-coupled hM3R in complex with iperoxo (local refinement)

Released:
Source organism: Homo sapiens
Related structures: EMD-27970

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-148928 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Muscarinic acetylcholine receptor M3 Chain: A
Molecule details ›
Chain: A
Length: 568 amino acids
Theoretical weight: 62.97 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P20309 (Residues: 46-590; Coverage: 62%)
Gene name: CHRM3
Sequence domains: 7 transmembrane receptor (rhodopsin family)

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.56Å
Relevant EMDB volumes: EMD-27970
Expression system: Spodoptera frugiperda