8ec0

Electron Microscopy
3.3Å resolution

III2IV respiratory supercomplex from Saccharomyces cerevisiae cardiolipin-lacking mutant

Released:

Function and Biology Details

Reactions catalysed:
Quinol + 2 ferricytochrome c(Side 2) = quinone + 2 ferrocytochrome c(Side 2) + 2 H(+)(Side 2)
4 ferrocytochrome c + O(2) + 8 H(+)(Side 1) = 4 ferricytochrome c + 4 H(2)O(Side 2)
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero 30-mer (preferred)
PDBe Complex ID:
PDB-CPX-216252 (preferred)
Entry contents:
21 distinct polypeptide molecules
Macromolecules (21 distinct):
Cytochrome b-c1 complex subunit 1, mitochondrial Chains: A, a
Molecule details ›
Chains: A, a
Length: 457 amino acids
Theoretical weight: 50.28 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P07256 (Residues: 1-457; Coverage: 100%)
Gene names: COR1, QCR1, YBL0403, YBL045C
Sequence domains:
Cytochrome b-c1 complex subunit 2, mitochondrial Chains: B, b
Molecule details ›
Chains: B, b
Length: 368 amino acids
Theoretical weight: 40.53 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P07257 (Residues: 1-368; Coverage: 100%)
Gene names: COR2, P9677.6, QCR2, UCR2, YPR191W
Sequence domains: Insulinase (Peptidase family M16)
Cytochrome b-c1 complex subunit Rieske, mitochondrial Chains: C, c
Cytochrome b-c1 complex subunit 9, mitochondrial Chains: E, e
Cytochrome b-c1 complex subunit 7, mitochondrial Chains: F, f
Cytochrome b-c1 complex subunit 6, mitochondrial Chains: G, g
Cytochrome b-c1 complex subunit 8, mitochondrial Chains: H, h
Cytochrome b Chains: J, j
Cytochrome c oxidase subunit 1 Chain: K
Cytochrome c1, heme protein, mitochondrial Chains: L, l
Cytochrome c oxidase subunit 8, mitochondrial Chain: M
Cytochrome c oxidase subunit 7, mitochondrial Chain: N
Cytochrome c oxidase subunit 3 Chain: O
Cytochrome c oxidase subunit 2 Chain: P
Cytochrome c oxidase subunit 6, mitochondrial Chain: Q
Cytochrome c oxidase subunit 9, mitochondrial Chain: R
Cytochrome c oxidase subunit 13, mitochondrial Chain: S
Cytochrome c oxidase subunit 4, mitochondrial Chain: T
Cytochrome c oxidase subunit 12, mitochondrial Chain: U
Cytochrome c oxidase subunit 26, mitochondrial Chain: V
Cytochrome c oxidase subunit 5A, mitochondrial Chain: W

Ligands and Environments

Experiments and Validation Details

Entry percentile scores
Resolution: 3.3Å
Relevant EMDB volumes: EMD-28011