8wtu

Electron Microscopy
2.7Å resolution

Cryo-EM structure of noradrenaline transporter in apo state

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-273409 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sodium-dependent noradrenaline transporter Chain: A
Molecule details ›
Chain: A
Length: 566 amino acids
Theoretical weight: 63.8 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P23975 (Residues: 52-617; Coverage: 92%)
Gene names: NAT1, NET1, SLC6A2, SLC6A5
Sequence domains: Sodium:neurotransmitter symporter family

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.7Å
Relevant EMDB volumes: EMD-37842
Expression system: Homo sapiens