Electron Microscopy Data Bank

EMD-12777

Single-particle
3.0 Å

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Deposition: 19/04/2021
Map released: 11/08/2021
Last modified: 06/10/2021

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EMD-12777

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Nanobody C5 bound to Spike

EMD-12777

Single-particle
3.0 Å
EMD-12777

3D View Gallery

Deposition: 19/04/2021
Map released: 11/08/2021
Last modified: 06/10/2021

Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

Sample Organism: Severe acute respiratory syndrome coronavirus 2, Vicugna pacos
Sample: nanobody complex
Fitted models: 7oan

Deposition Authors: Naismith JH, Weckener M

A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19.

Huo J , Mikolajek H, Le Bas A , Clark JJ , Sharma P, Kipar A, Dormon J, Norman C , Weckener M, Clare DK, Harrison PJ, Tree JA, Buttigieg KR, Salguero FJ, Watson R , Knott D, Carnell O , Ngabo D , Elmore MJ , Fotheringham S, Harding A, Moynie L , Ward PN , Dumoux M , Prince T , Hall Y, Hiscox JA, Owen A , James W , Carroll MW, Stewart JP , Naismith JH , Owens RJ
(2021) Nat Commun , 12 , 5469 - 5469

PUBMED: 34552091
DOI: doi:10.1038/s41467-021-25480-z
ISSN: 2041-1723

Secondary citations:

Huo J, Mikolajek H, Le Bas A, Clark J, Sharma P, Kipar A, Dormon J, Norman C, Weckener M, Clare D, Harrison P, Tree J, Buttigieg K, Salguero F, Watson R, Knott D, Carnell O, Ngabo D, Elmore M, Fotheringham S, Harding A, Ward P, Moynie L, Dumoux M, Hall Y, Hiscox J, Owen A, James W, Carroll M, Stewart J, Naismith J & Owens R. (2021) A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19.