EMD-20817
Cryo-EM structure of HIV-1 neutralizing antibody DH270 UCA3 in complex with CH848 10.17DT Env
EMD-20817
Single-particle4.2 Å
Deposition: 09/10/2019Map released: 18/12/2019
Last modified: 06/11/2024
Sample Organism:
Human immunodeficiency virus 1,
Homo sapiens
Sample: DH270 UCA3 Fab bound to HIV-1 Env CH848 10.17DT
Fitted models: 6um5
Deposition Authors: Acharya P
,
Henderson RC
Sample: DH270 UCA3 Fab bound to HIV-1 Env CH848 10.17DT
Fitted models: 6um5
Deposition Authors: Acharya P
,
Henderson RC
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.
Saunders KO ,
Wiehe K ,
Tian M ,
Acharya P ,
Bradley T ,
Alam SM ,
Go EP,
Scearce R ,
Sutherland L ,
Henderson R ,
Hsu AL ,
Borgnia MJ ,
Chen H,
Lu X,
Wu NR ,
Watts B ,
Jiang C,
Easterhoff D,
Cheng HL,
McGovern K ,
Waddicor P ,
Chapdelaine-Williams A,
Eaton A ,
Zhang J ,
Rountree W ,
Verkoczy L,
Tomai M ,
Lewis MG ,
Desaire HR,
Edwards RJ ,
Cain DW ,
Bonsignori M ,
Montefiori D ,
Alt FW ,
Haynes BF
(2019) Science , 366
,
Wiehe K ,
Tian M ,
Acharya P ,
Bradley T ,
Alam SM ,
Go EP,
Scearce R ,
Sutherland L ,
Henderson R ,
Hsu AL ,
Borgnia MJ ,
Chen H,
Lu X,
Wu NR ,
Watts B ,
Jiang C,
Easterhoff D,
Cheng HL,
McGovern K ,
Waddicor P ,
Chapdelaine-Williams A,
Eaton A ,
Zhang J ,
Rountree W ,
Verkoczy L,
Tomai M ,
Lewis MG ,
Desaire HR,
Edwards RJ ,
Cain DW ,
Bonsignori M ,
Montefiori D ,
Alt FW ,
Haynes BF
(2019) Science , 366