EMD-34919

Single-particle
3.1 Å
EMD-34919
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Deposition: 08/12/2022
Map released: 19/07/2023
Last modified: 03/07/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-34919
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8hnv summary report (pdf.gz) Map and 8hnv FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of HpaCas9-sgRNA-dsDNA in the presence of AcrIIC4

EMD-34919

Single-particle
3.1 Å
EMD-34919
3D View Gallery
Deposition: 08/12/2022
Map released: 19/07/2023
Last modified: 03/07/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Haemophilus parainfluenzae, synthetic construct
Sample: Complex of HpaCas9-sgRNA-DNA in the presence of AcrIIC4
Fitted models: 8hnv

Deposition Authors: Sun W , Cheng Z , Wang J, Yang X, Wang Y
AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Sun W , Cheng Z , Wang J, Yang J , Li X , Wang J, Chen M, Yang X, Sheng G, Lou J, Wang Y
(2023) PNAS , 120 , e2303675120 - e2303675120
PUBMED: 37494395
DOI: doi:10.1073/pnas.2303675120
ISSN: 1091-6490
ASTM: PNASA6