› 101d

X-ray diffraction
2.25Å resolution

REFINEMENT OF NETROPSIN BOUND TO DNA: BIAS AND FEEDBACK IN ELECTRON DENSITY MAP INTERPRETATION

Released:
DOI: 10.2210/pdb101d/pdb
PDB entry 101d coloured by chain, front view.
PDB entry 101d coloured by chain, side view.
PDB entry 101d coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Refinement of netropsin bound to DNA: bias and feedback in electron density map interpretation.
Goodsell DS, Kopka ML, Dickerson RE
Biochemistry 34 4983-93 (1995)
PMID: 7711020

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113293 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(CBR)P*GP*CP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 12 nucleotides
Theoretical weight: 3.74 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand NT 1 x NT
1 modified residue:
Ligand CBR 2 x CBR

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 24.27Å b: 39.62Å c: 63.57Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.163 not available 0.252
Expression system: Not provided

Quick links

Citations

4 review citations

Synthetic DNA minor groove-binding drugs.
Reddy et al. (1999)
3 more

17 mentions without citation

Photochemistry of flavonoids.
Sisa et al. (2010)
16 more