› 1dzd

Solution NMR

High resolution structure of acidic fibroblast growth factor (27-154), 24 NMR structures

Released:
DOI: 10.2210/pdb1dzd/pdb
PDB entry 1dzd coloured by chain, ensemble of 24 models, front view.
PDB entry 1dzd coloured by chain, ensemble of 24 models, side view.
PDB entry 1dzd coloured by chain, ensemble of 24 models, top view.
Source organism: Homo sapiens
Primary publication:
1H NMR structural characterization of a nonmitogenic, vasodilatory, ischemia-protector and neuromodulatory acidic fibroblast growth factor.
Lozano RM, Pineda-Lucena A, Gonzalez C, Angeles Jiménez M, Cuevas P, Redondo-Horcajo M, Sanz JM, Rico M, Giménez-Gallego G
Biochemistry 39 4982-93 (2000)
PMID: 10819962

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138603 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor 1 Chain: A
Molecule details ›
Chain: A
Length: 127 amino acids
Theoretical weight: 14.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05230 (Residues: 29-155; Coverage: 82%)
Gene names: FGF1, FGFA
Sequence domains: Fibroblast growth factor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: RESTRAINED MOLECULAR DYNAMICS
Expression system: Escherichia coli

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Citations

1 review citation

Fibroblast growth factors in myocardial ischemia / reperfusion injury and ischemic preconditioning.
Cuevas et al. (2001)
16 other articles